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Medical Professionals/Persons with CFIDS
CFIDS Research Review

UPDATED: 01/01/98

Virology

Berelowitz, GJ., Burgess, AP., Thanabalasingham, T., Murray-Lyon, IM., and Wright, DJ. Post-hepatitis syndrome revisited. J Virol Hepat, 1995, 2(3):133-138.

Bowles, NE., Bayston, TA., Zhang, HY., Doyle, D., Lane, RJ., Cunningham, L., and Archard, LC. Persistence of enterovirus RNA in muscle biopsy samples suggests that some cases of chronic fatigue syndrome result from a previous, inflammatory viral myopathy. J Med, 24(2-3):145-160.

Buchwald, D., Ashley, RL., Pearlman, T., Kith, P. and Komaroff, AL. Viral serologies in patients with chronic fatigue syndrome. Journal of Medical Virology, 1996, 50 (1):25-30.

Dowsett, EG., Ramsay, AM., McCartney, RA., and Bell, EJ. Myalgic encephalomyelitis - a persistent enteroviral infection? Postgrad Med J, July 1990, 66(777):526-530.

Hotchin, NA., Read, R., Smith, DG., and Crawford, DH. Active Epstein-Barr virus infection in post-viral fatigue syndrome. J Infect, Mar 1989, 18(2):143-150.

Levy, JA. Viral studies of chronic fatigue syndrome. Clinical Infectious Diseases, 1994, 18:5117-5120

McArdle, A., McArdle, F., Jackson, MJ., Page, SF., Fahal, L., and Edwards, RHT. Investigation by polymerase chain reaction of enteroviral infection in patients with chronic fatigue syndrome. Clinical Science, 1996, 90: 295-300.

Wagner, D., Krueger, GRF., Ablishi, DV., and Whitman, JE. Chronic fatigue syndrome (CFS): a critical evaluation of testing for active human herpesvirus-6 (HHV-6) infection: review of data for 107 cases. Journal of Chronic Fatigue Syndrome, 1996, 2(4):3-16.


Immunology

Buchwald, D., Wener, MH., Pearlman, T., and Kith, P. Markers of inflammation and immune activation in chronic fatigue and chronic fatigue syndrome. Journal of Rheumatology, 1997, 24(2):372-376.

Buchwald, D., Cheney, P., Peterson, DL., Henry, B., Wormsley, SB., Geiger, A., Ablashi, DV., Salahuddin, SZ., Saxinger, C., Biddle, R., Kikinus, R., Jolesz, FA., Folks, T., Balachandran, N., Peter, JB., Gallo, RC., and Komaroff, AL. A chronic illness characterized by fatigue, neurologica and immunologic disorders, and active human herpesvirus type 6 infection. Annals of Int Med, 1992, 116:103-113.

Buchwald, D., Cheney, P., Peterson, DI., Henry, B., Wormsley, SB., Geiger, A., Ablashi, DV., Salahuddin, SZ., Saxinger, C., Biddle, R., Kikinis, R., Jolesz, FA., Folks, T., Balachandran, N., Peter, JB., Gallo, RC., and Komaroff, AL. A chronic illness characterized by fatigue, neurologic and immunologic disorders, and active human herpesvirus type 6 infection. Annals of Internal Medicine, 1992, 116:103-113.

Caliguiri, M., Murray, C., Buchwald, D., Levine, H., Cheney, P., Peterson, D., Komaroff, AL., and Ritz, J. Phenotypic and functional deficiency of natural killer cells in patients with chronic fatigue syndrome. J Immunology, 1987, 139:3306-3313.

Chao, CC., Janoff, EN., Ru, SX., Thomas, K., Gallagher, M., Tsang, M., and Peterson, PK. Altered cytokine release in peripheral blood mononuclear cell cultures from patients with chronic fatigue syndrome. Cytokine, 1991, 3:292-298.

Hilgers, A., and Frank J. Chronic fatigue syndrome: evaluation of a 30-criteria-score and correlation with immune activation. Journal of Chronic Fatigue Syndrome, 2(4):35-47.

Ho-Yen, DO., Billington, RW., and Urquhart, J. Natural killer cells and the post viral fatigue syndrome. Scan J Inf Dis, 1991, 23(6):711-716.

Klimas, N., Salvato, F., Morgan, R., and Fletcher, MA. Immunological abnormalities in chronic fatigue syndrome. J Clin Microbiology, 1990, 28(6):1403-1410.

Konstantinov, K., von Milkecz, A., Buchwald, D., Jones, J., Gerace, L., and Tan, EM. Autoantibodies to nuclear envelope antigens in chronic fatigue syndrome. Journal of Clinical Investigation, 1996, 98:1888-1896.

Mawle, AC., Nisenbaum, R., Dobbins, JG., Gary, HE., Stewart, JA., Reyes, M., Steele, L., Schmid, DS., and Reeves, WC. Immune responses associated with chronic fatigue syndrome: a case-control study. Journal of Infectious Diseases, 1997, 175(1):136-141.

Morrison, LJ., Behan, WH., and Behan, PO. Changes in natural killer cell phenotype in patients with post-viral fatigue syndrome. Clin Exp Immunol, Mar 1991, 83(3):441-446.

Peakman, M., Deale, A., Field, R., Mahalingham, M., and Wessely, S. Clinical improvement in chronic fatigue is not associated with lymphocyte subsets of function of activation. Clinical Immunology and Immunopathology, 1997, 82(1):83-91.

Sheng, WS., Hu, SX., Lamkin, A., Peterson, PK., and Chao, CC. Susceptibility to immunologically mediated fatigue in C57/BL/6 versus Balb/c mice. Clinical Immunology and Immunopathology, 1996, 81(2):161-167.

Straus, S., Fritz, J., Dale, J., Gould, B., and Strober, W. Lymphocyte phenotype and function in chronic fatigue syndrome. J Clin Immunology, 1993, 13:3040.

Steinberg, P., Pheley, A., and Peterson, PK. Influence of immediate hypersensitivity skin reactions on delayed reactions in patients with chronic fatigue syndrome. Journal of Allergy and Clinical Immunology, 1996, 98(6):1126-1128.

Suhadolnik, RJ., Peterson, DL., O'Brien, K., Cheney, PR., Herst, CVT., Reichenbach, NL., Ning, K., Horvath, SE., Iacono, KT., Adelson, ME., DeMeirleir, K., DeBecker, P., Charubala, R., and Pfleiderer, W. Biochemical evidence for a novel low molecular weight 2-5A-dependent RNaseL in chronic fatigue syndrome. Journal of Interferon and Cytokine Research, July 1997(17):377-385.

Suhadolnik, RJ., Reichenbach, NL., Hitzges, P., Adelson, ME., Peterson, DL., Cheney, PR., Salvato, P., Thompson, C., Loveless, M., Muller, WEG., Schroder, HC., Strayner, DR., and Carter, WA. Changes in the 2-5A synthetase/RNase L antiviral pathway in a controlled clinical trial with Poly(1)-Poly(Ct2U) in chronic fatigue syndrome. In Vivo, 1994, 8:599-604.

Von Mikecz, A., Konstantinov, K., Buchwald, DS., Gerace, L., and Tan, EM. High frequency of autoantibodies to insoluble cellular antigens in patients with chronic fatigue syndrome. Arthritis and Rheumatism, 1997, 40(2):295-305.


Neurology

Goldberg, MD., Mena, I., and Darcourt, J. NeuroSPECT findings in children with chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome, 1997 ,3(1):61-67.


Physiology, Neurophysiology, and Neuroendocrinology

Arnold, DL., Bore, PJ., Radda, GK., Styles, P., and Taylor, DJ. Excessive intracellular acidosis of skeletal muscle on exercise in a patient with a post-viral exhaustion/fatigue syndrome: a 31P nuclear magnetic resonance study. Lancet, 23 June 1984, 1(8391):1367-1369.

Chaudhurt, A., Majeed, T., Dinan, T., and Behan, PO. Chrinic fatigue syndrome: a disorder of central cholinerc transmission. Journal of Chronic Fatigue Syndrome, 1997, 3(1):3-16.

Connolly, S., SMith, DG., Doyle, D., and Fowler, CJ. Chronic fatigue: electromyographic and neuropathological evaluation. J Neurol, July 1993, 240(7):435-438.

Demitrack, M., Dale, J., Straus, SA., Laue, L., Listwak, S., Kruesi, M., Chrousos, O., and Gold, P. Evidence for impaired activation of the hypothalamic-pituitary-adrenal axis in patients with chronic fatigue syndrome. J Clin Endocrin, 1991, 73:122-124.

Jamal, GA., and Hansen, S. Postviral fatigue syndrome: evidence for underlying organic disturbance in the muscle fibre. Eur Neurol, 1989, 29(5):273-276.

Jamal, GA., and Hansen, S. Electrophysiological studies in post-viral fatigue syndrome. J Neurol Neurosurg Psychiatry, July 1985, 48(7):691-694.

James, LC, and Folen, RA. EEG biofeedback as a treatment for chronic fatigue syndrome: a controlled case report. Behavioral Medicine, 1996, 22(2):77-81.

McGregor, NR., Dunstan, RH., Butt, HL., Roberts, TK., Klineberg, IJ., and Zerbes, M. A preliminary assessment of the association of SCL-90-R psychological inventory responses with changes in urinary metabolites in patients with chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome, 1997, 3(1):17-37.

Preedy, VR., Smith, DG., Salisbury, JR., and Peters, TJ. Biochemical and muscle studies in patients with acute onset post-viral fatigue syndrome. J Clin Pathol, Aug 1993, 46(8):722-726.

Samii, A., Wassermann, EM., Ikoma, E., Mercuri, B., George, MS., O'Fallon, A., Dale, JK., Straus, SE., and Hallett, M. Decreased postexercise facilitation of motor evoked potentials in patients with chronic fatigue syndrome or depression. Neurology, 1996, 47(6):1410-1414.

Williams, G., Pirmohamed, J., Minors, D., Waterhouse, J., Buchan, I., Arendt, J., and Edwards, RHT. Dissociation of body-temperature and melatonin secretion circadian rhythms in patients with chronic fatigue syndrome. Clinical Physiology, 1996, 16(4):327-337.


Psychology, Neuropsychology, and Psychiatry

DeLuca, J., Johnson, SK., Ellis, SP., and Natelson, BH. Cognitive functioning is impaired in patients with chronic fatigue syndrome devoid of psychiatric disease. Journal of Neurology, Neurosurgery, and Psychiatry, 1997, 62:151-155.

Levine, Paul, ed. "Prodeedings from the 1994 Fort Lauderdale CFS Scientific Meeting," Journal of Psychiatric Research (January 1997).

Michaels, V., Cluydis, R., Fischler, B.,, Hoffmann, G., LeBon, O., and DeMeireir, K. Cognitive functioning in patients with chronic fatigue syndrome. Journal of Clinical and Experimental Neuropsychology, 1996, 18(5):666-677.


Epidemiology

Bombardier, CH., and Buchwald, D. Chronic fatigue, chronic fatigue syndrome, and fibromyalgia: Disability and health-care use. Medical Care, 1996, 34(9):924-930.

Buchwald, D., Umali, J., Pearlman, T., Kith, P., Ashley, R., and Wener, M. Postinfectious chronic fatigue: a distinct syndrome? Clinical Infectious Diseases, 1996, 23(2):385-387.

Buchwald, D., Pearlman, T., Umali, J., Schmaling, K., and Katon, W. Functional status in patients with chronic fatigue syndrome, other fatiguing illnesses, and healthy individuals. American Journal of Medicine, 1996, 101: 364-370. Buchwald, D., and Komaroff, A. Review of laboratory findings for patients with chronic fatigue syndrome. Rev Inf Dis, 1991, 13(Suppl. 1):512-518.

Fukuda, K., Straus, SA., Hickie, I., Sharpe, MC., Dobbins, JG., and Komaroff, A. The chronic fatigue syndrome: a comprehensive approach to its definition and study. Annals Int Med, 1994, 121:953-959.

Holmes, G., et al. Chronic fatigue syndrome: a working case definition. Annals Int Med, 1988, 108:387-389.

Jason, L.A., Ropacki, MT., Santoro, NB., Richman, JA., Heatherly, W., Taylor, R., Ferrari, JR., Haney-Davis, TM., Rademaker, A., Dupuis, J., Golding, J., Pliopys, AV., and Pliopys, S. A screening instrument for chronic fatigue syndorme: reliability and validity. Journal of Chronic Fatigue Syndrome, 1997, 3(1):39-59.

Komaroff, AL., Fagioli, LR., Doolittle, TH., Gandek, B., Gleit, MA., Guerriero, RT., Kornish, J., Ware, NC., Ware, JE., and Bates, DW. Health status in patients with chronic fatigue syndrome and in general population and disease comparison groups. American Journal of Medicine, 1996, 101(3):281-290.

Lerner, AM., Zervos, M., Dworkin., HJ., Chang, CH., O'Neill, W. A unified theory of the cause of chronic fatigue syndrome. Infectious Diseases in Clinical Practice, 1997 (6):239-243.

Levine, PH., Dale, JK., Benson-Grigg, E., Fritz, S. Gruggerman, S., and Straus, SE. A cluster of cases of chronic fatigue and chronic fatigue syndrome: clinical and immunological studies. Clinical Infectious Diseases, 1996, 23: 408-409.

Reyes, M., Dobbins, JG., Mawle, AC., Steele, L., Gary, HE., Malani, H., Schmid, S., Fakuda, K., Stewart, J., Nisenbaum, R., and Reeves, WC. Risk factors for chronic fatigue syndrome: a case-control study. Journal of Chronic Fatigue Syndrome, 1996, 2(4):17-33.


Rheumatology

Buchwald, et al. Insulin-like Growth Factor-1 (Somatomedin C) levels in chronic fatigue syndrome and fibromyalgia. Journal of Rheumatology, 1996, 23(4):739-742.


Sociology

Ax, S., Gregg, VH., and Jones, D. Chronic fatigue syndrome: sufferers evaluation of medical support. Journal of the Royal Society of Medicine, 1997, 90:250-254.

Cooper, L. Myalgic encephalomyelitis and the medical encounter. Sociology of Health and Illness, 1997, 19(2):186-207.


Therapeutics

Chalder, T., Butler, S., and Wessely, S. In-patient treatment of chronic fatigue syndrome. Behavioral and Cognitive Psychotherapy, 1996, 24:351-365.

Deale, A., Chalder, T., Marks, I., and Wessely, S. Cognitive behavior therapy for chronic fatigue syndrome: a randomized controlled trial. American Journal of Psychiatry, 1997, 154(3):408-414.

Lerner, AM., Zervos, M., Dworkan, HJ., Chang, CH., Fitzgerald, JY., Goldstein, J., Lawrie-Hoppen, C., Franklin, B., Krotkin, SM., Brodsky, M., Walsh, D., and O'Neill, W. New cardiomyopathy: pilot study of intraenous ganciclovir in a subset of the chronic fatigue syndrome. Infectious Diseases in Clinical Practice, 1997, 6(2):110-117.

Natelson, BH., Chen, J., Pareja, J., Ellis, SP., Policastro, T and Findley, TW. Randomized, double-blind, controlled, placebo-phase in trial with low dose phenelzine in the chronic fatigue syndrome. Psychopharmacology, 1996, 124:226-230.

See, DM., and Tilles, TM. Alpha interferon treatment of patients with chronic fatigue syndrome. Immunological Investigations, 1996, 25(1-2):153-164.


Clinical Practice and Treatment

Behan, PO., Behan, WM., and Horrobin, D. Effect of high doses of essential fatty acids on the postviral fatigue syndrome. Acta Neurol Scand, Sept 1990, 82(3):209-216.

Kuratsune, H., Yamaguti, K., Hattori, H., Tazawa, H., Takahashi, M., Yamanishi, K., and Kitani, T. Symptoms, signs, and laboratory findings with chronic fatigue syndrome <[>article in Japanese]. Nippon Rinsho, Nov 1992, 50(11):2665-2672.


Reviews

Behan, PO., and Bakheit, AM. Clinical spectrum of postviral fatigue syndrome. Br Med Bull, Oct 1991, 47(4):793-808.

Pheby, D. Chronic fatigue syndromke: a challenge to the clinical professions. Psychotherapy, 1997, 83(2):25-56.

Scott, LV., and Dinan, TG. The neuroendocrinology of chronic fatigue syndrome. Journal of Chronic Fatigue Syndrome, 1996, 2(4):29-59.

Wearden, AJ., and Appleby, L. Research on cognitive complaints and cognitive functioning in patients with chronic fatigue syndrome (CFS): what conclusions can we draw? Journal of Psychosomatic Research, 1996, 41(3):197-211.


Miscellaneous

Behan, PO. Chronic fatigue syndrome as a delayed reaction to chronic low-dose organophosphate exposure. Journal of Nutritional and Environmental Medicine, 1996, 6:341-350.

Borok, G. Committee to investigate chronic fatigue syndrome. South African Medical Journal, 1996, 86(10):1301.

Fry, AM., and Martin, M,. Fatigue in chronic fatigue syndrome: a cognitive phenomenon? Journal of Psychosomatic Research, 1996, 41(5):415-426.

Gombrone, JE., Gorard, DA., Dewsnap, PA., Libby, GW., and Farthing, MJG. Prevalence of irritable bowel syndrome in chronic fatigue. Journal of the Royal Colleges of Physicians of London, 1996, 30(6):512-513.

Lindh, G., Samuelson, A., Hedlund, KO., Evangard, B., Lindquist, L., and Ehrnst, A. No finding of enteroviruses in Swedish patients with chronic fatigue syndrome. Scandanavian Journal of Infectious Diseases, 1996, 28(3):305-307.

Norregarrd, et al. Exercise training in treatment of fibromyalgia. Journal of Musculoskeletal Pain, 1997, 5(1):71-79.

Parker, et al. Chronic fatigue syndrome and the athlete. Sports Medicine Training and Rehabilitation, 1996 (6):269-278.

Patarca, R., Bell, IR., and Fletcher, MA. Pteridines and neuroimmune function and pathology. Journal of Chronic Fatigue Syndrome, 1997, 3(1):69-86.

Pearn, JH., Chronic fatigue syndrome: chronic ciquatera poisoning as a differential diagnosis. Medical Journal of Australia, 1997, 166 (6):309-310.

Shepherd, C. Chronic fatigue syndrome [Letter]. Lancet, 1997, 349:57-58.

Shepherd, C. Disagreements still exist over the chronic fatigue syndrome. British Medical Journal, 1997, 314: 146.

Sutton, GC. 'Too tired to go to the support group': a health needs assessment of myalgic encephalomyelitis. Journal of Public Health Medicine, 1996, 18(3):343-349.

Various. Chronic fatigue syndrome. Lancet, 1996, 348:1384-1385.

Wiebe, E. N of 1 trials: Managing patients with chronic fatigue syndrome: two case reports. Canadian Family Physician, 1996, 42:2214-2217.


Research on Other [Possibly Related] Disorders

Bode, L., Dietrich, DE., Stoyloff, R., Emirhc, HM., and Ludwig, H. Amantadine and human Borna disease virus in vitro and in vivo in an infected patient with bipolar depression. Lancet, 1997, 349:178-179.

Brregaard, J., Lykkegaard, JJ., Mehlsen, J., and Danneskiold-Sams, B., Exercise training in treatment of fibromyalgia. Journal of Musculaskeletal Pain, 1997, 5(1):71-79.

Bruno, RL., Zimmerman, JR., Creange, SJ., Lewis, T., Molzen, T., and Frick, NM. Bromocriptine in the treatment of post-polio fatigue: A pilot study with implications for the pathophysiology of fatigue. American Journal of Physical Medicine and Rehabilitation, 1996, 75:340-347.

Buskila, et al. Fibromyalgia Syndrome in Children: An Outcome Study. Journal of Rheumatology, 1995, 22(3):525-528.

Buskila, et al. Fibromyalgia in Children: Lessons from Assessing Non-articular Tenderness. Journal of Rheumatology, 1996, 23(12):2017-2019.

Dalakas, MC. Pathogenetic mechanisms of post-polio syndrome: morphological, electrophysiological, virological, and immunological correlations. Annals NY Acad Sci, May 1995, 753:167-185.

Gow, JW., Behan, WMH., Cash,, P., Simpson, K., and Behan, PO. Genomic and template RNA transcription in a model of persistent enteroviral infection. Journal of Neurovirology, 1997, 3:76-82.

Gresty, M., and Brookes, G. Deafness and vertigo. Current Opinion in Neurology, 1997, 10:36-42.

Luxon, LM. Vertigo: new approaches to diagnosis and management. British Journal of Hospital Medicine, 1996, 56(10):519-520, 537-541.


Books

Bell, David. The Doctor's Guide to Chronic Fatigue Syndrome. Boston: Addison-Wessley Publishing Group, 1994.

Courmel, K. A Companion Volume to Dr. Jay Goldstein's Betrayal by the Brain. Binghamton, NY: Haworth Press, 1996.

Dayger,m Kendra. Review of Mainstream CFIDS Research in the USA. Rochester: CFIDS Rochester Research Project, 1992.

Dayger, Kendra. Ft. Lauderdale Notebook Series: From a Series of Notebooks Chronicling the Chronic Fatigue Immune Dysfunction Syndrome International Research Conference. Rochester: CFIDS Rochester Research Project, 1995. [Available from CFIDS Rochester Research Project, 623 Eastbrooke Lane, Rochester, NY 14618].

Goldstein, JA. Betrayal by the Brain. Binghamton, NY: Haworth Press, 1996.

Goldstein, JA. Chronic Fatigue Syndrome: The Limbic Hypothesis. Binghamton, NY: Haworth Press, 1992.

Hyde, Byron M. The Clinical and Scientiric Basis of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome. Ottawa, Ontario: The Nightingale Research Foundation, 1992. [Available from the Nightingale Research Foundation, Ontario, Canada].

Klonoff, EA., and Landrine, H. Preventing Misdiagnosis of Women: A Guide to Physical Disorders that have Psychiatric Symptoms. London: Sage Publications, 1997.

Yehuda, S., and Mostofsky, DI(eds). Chronic Fatigue Syndrome. New York: Plenum Press, 1997.


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